MBLs, Rather Than Efflux Pumps, Led to Carbapenem Resistance in Fosfomycin and Aztreonam/Avibactam Resistant Elizabethkingia anophelis
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چکیده
منابع مشابه
Title : Fosfomycin Susceptibility in Carbapenem - Resistant
Title: Fosfomycin Susceptibility in Carbapenem-Resistant 1 Enterobacteriaceae from Germany 2 Running title: Fosfomycin Susceptibility in Enterobacteriaceae 3 4
متن کاملBacterial Multidrug Efflux Pumps: Much More Than Antibiotic Resistance Determinants
Bacterial multidrug efflux pumps are antibiotic resistance determinants present in all microorganisms. With few exceptions, they are chromosomally encoded and present a conserved organization both at the genetic and at the protein levels. In addition, most, if not all, strains of a given bacterial species present the same chromosomally-encoded efflux pumps. Altogether this indicates that multid...
متن کاملFosfomycin susceptibility in carbapenem-resistant Enterobacteriaceae from Germany.
Due to the increase in multidrug-resistant Enterobacteriaceae, the interest in older antimicrobial agents, like fosfomycin, has increased. In this study, we used agar dilution for testing susceptibilities to fosfomycin in a collection of 107 carbapenem-nonsusceptible Enterobacteriaceae isolates, of which 80 produced various types of carbapenemases, including KPC, VIM, NDM, and OXA-48. Overall, ...
متن کاملResistance to Antimicrobials Mediated by Efflux Pumps in Staphylococcus aureus
Resistance mediated by efflux has been recognized in Staphylococcus aureus in the last few decades, although its clinical relevance has only been recognized recently. The existence of only a few studies on the individual and overall contribution of efflux to resistance phenotypes associated with the need of well-established methods to assess efflux activity in clinical isolates contributes grea...
متن کاملElizabethkingia anophelis: molecular manipulation and interactions with mosquito hosts.
Flavobacteria (members of the family Flavobacteriaceae) dominate the bacterial community in the Anopheles mosquito midgut. One such commensal, Elizabethkingia anophelis, is closely associated with Anopheles mosquitoes through transstadial persistence (i.e., from one life stage to the next); these and other properties favor its development for paratransgenic applications in control of malaria pa...
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ژورنال
عنوان ژورنال: Infection and Drug Resistance
سال: 2021
ISSN: 1178-6973
DOI: 10.2147/idr.s294149